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alpha Sarcoglycan antibody [Ad1/20A6]

Anti-alpha Sarcoglycan antibody [Ad1/20A6] used in IHC (Frozen sections) (IHC-Fr). GTX01939

Cat. No. GTX01939

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 Ad1/20A6

Isotype

 IgG1

Application

 IHC-Fr

Reactivity

 Human, Mouse, Rat, Rabbit, Hamster, Pig
Package
500 μl ($599)
See all alpha Sarcoglycan products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-Fr 1:100–1:200

Note :

IHC-Fr
Freeze specimen tissue blocks in isopentane chilled in liquid nitrogen.
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

Product Note

We do not recommend use of this product for Chicken samples.

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Rabbit

Immunogen

Fusion protein containing amino acids 217 to 289 of the rabbit adhalin sequence (Roberds SL et al., 1993).

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

sarcoglycan alpha , 50DAG , ADL , DAG2 , DMDA2 , LGMD2D , LGMDR3 , SCARMD1 , adhalin

Cellular Localization

Cytoplasm, cytoskeleton

Background

This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

Database

Research Area

DATA IMAGES

Anti-alpha Sarcoglycan antibody [Ad1/20A6] used in IHC (Frozen sections) (IHC-Fr). GTX01939

GTX01939 IHC-Fr Image

IHC-Fr analysis of transverse section of skeletal muscle fibers using GTX01939 alpha Sarcoglycan antibody [Ad1/20A6]. Note the demonstration of localized Alpha Sarcoglycan to the sarcolemma of the muscle fibers.

REFERENCE

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REVIEW

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Package List Price ($)
$ 599