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alpha Synuclein antibody [2A7]

Anti-alpha Synuclein antibody [2A7] used in Western Blot (WB). GTX04298
Anti-alpha Synuclein antibody [2A7] used in IHC (Free Floating) (IHC (Free Floating)). GTX04298

Cat. No. GTX04298

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 2A7

Isotype

 IgG1

Application

 WB, ICC/IF, IHC (Free Floating)

Reactivity

 Human, Mouse, Rat, Bovine, Pig
Package
100 μl ($399)
See all alpha Synuclein products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
ICC/IF 1:1000
IHC (Free Floating) Assay dependent
Not tested in other applications.

Calculated MW

14 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% glycerol

Preservative

5mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full length human recombinant protein expressed in and purified from E. coli

Purification

Purified IgG1

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

synuclein alpha , NACP , PARK1 , PARK4 , PD1

Cellular Localization

Cytoplasm , Membrane , Nucleus , Cell junction, synapse , Secreted

Background

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]

Database

Research Area

DATA IMAGES

Anti-alpha Synuclein antibody [2A7] used in Western Blot (WB). GTX04298

GTX04298 WB Image

WB analysis of various sample lysates using GTX04298 alpha Synuclein antibody [2A7].
Lane 1 : Molecular marker
Lane 2 : Rat brain tissue lysate
Lane 3 : Rat spinal cord tissue lysate
Dilution : 1:1000

Anti-alpha Synuclein antibody [2A7] used in IHC (Free Floating) (IHC (Free Floating)). GTX04298

GTX04298 IHC (Free Floating) Image

IHC (Free Floating) analysis of PFA-fixed rat cerebellum tissue using GTX04298 alpha Synuclein antibody [2A7].
Red : Primary antibody
Green : GFAP
Blue : Hoechst
Dilution : 1:1000

REFERENCE

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REVIEW

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Package List Price ($)
$ 399