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alpha Synuclein antibody

Anti-alpha Synuclein antibody used in Immunoprecipitation (IP). GTX02343
Anti-alpha Synuclein antibody used in Western Blot (WB). GTX02343

Cat No. GTX02343

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IP

Reactivity

Human
Package
100 μl ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:2000
IP 1-4 μl/mg of lysate
Not tested in other applications.

Calculated MW

14 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.2 μm filtered PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant Human SNCA / alpha-Synuclein protein

Purification

Purified by Protein A and Antigen Affinity

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

synuclein alpha , NACP , PARK1 , PARK4 , PD1

Cellular Localization

Cytoplasm , Membrane , Nucleus , Cell junction, synapse , Secreted

Background

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]

Database

Research Area

DATA IMAGES

Anti-alpha Synuclein antibody used in Immunoprecipitation (IP). GTX02343

GTX02343 IP Image

IP analysis of HeLa whole cell lysate using GTX02343 alpha Synuclein antibody.
IP antibody : 2 μl per 0.5 mg total whole cell lysate
Dilution : 1:100
50 % Protein G agarose : 15 μl

Anti-alpha Synuclein antibody used in Western Blot (WB). GTX02343

GTX02343 WB Image

WB analysis of various samples using GTX02343 alpha Synuclein antibody.
Lane A : 293T whole cell lysate
Lane B : SH-SY-5Y whole cell lysate
Dilution : 1:500
Loading : 30 μg

REFERENCE

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REVIEW

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