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alpha Synuclein antibody

Anti-alpha Synuclein antibody used in IHC (Paraffin sections) (IHC-P). GTX31928
Anti-alpha Synuclein antibody used in Western Blot (WB). GTX31928
Anti-alpha Synuclein antibody used in IHC (Paraffin sections) (IHC-P). GTX31928
Anti-alpha Synuclein antibody used in Western Blot (WB). GTX31928

Cat No. GTX31928

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, ELISA

Reactivity

Human, Mouse, Rat
Package
100 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

14 kDa. ( Note )

Positive Control

Mouse Cerebellum Tissue Lysate(GTX24021)

PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

alpha Synuclein antibody was raised against a 19 amino acid peptide near the carboxy terminus of human alpha Synuclein.The immunogen is located within the last 50 amino acids of alpha Synuclein.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

synuclein alpha , NACP , PARK1 , PARK4 , PD1

Cellular Localization

Cytoplasm,Membrane,Nucleus,Cell junction, synapse,Secreted

Background

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009]

Database

Research Area

DATA IMAGES

Anti-alpha Synuclein antibody used in IHC (Paraffin sections) (IHC-P). GTX31928

GTX31928 IHC-P Image

IHC-P analysis of rat brain tissue using GTX31928 alpha Synuclein antibody.
Working concentration : 20 μg/ml

Anti-alpha Synuclein antibody used in Western Blot (WB). GTX31928

GTX31928 WB Image

WB analysis of mouse cerebellum tissue lysate using GTX31928 alpha Synuclein antibody.
Working concentration : 1 μg/ml

Anti-alpha Synuclein antibody used in IHC (Paraffin sections) (IHC-P). GTX31928

GTX31928 IHC-P Image

IHC-P analysis of rat brain tissue using GTX31928 alpha Synuclein antibody.
Working concentration : 5 μg/ml

Anti-alpha Synuclein antibody used in Western Blot (WB). GTX31928

GTX31928 WB Image

WB analysis of 1 ng human SNCA recombinant protein using GTX31928 alpha Synuclein antibody.
Working concentration : 1 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339