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alpha Synuclein (phospho Tyr125) antibody

Anti-alpha Synuclein (phospho Tyr125) antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX50284
Anti-alpha Synuclein (phospho Tyr125) antibody used in Western Blot (WB). GTX50284

Cat No. GTX50284

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF

Reactivity

Human, Mouse
Package
100 μl ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:1000
ICC/IF 1:100-1:200
Not tested in other applications.

Calculated MW

14 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH 7.4, 150mM NaCl, 0.02% sodium azide, 50% glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide sequence around phosphorylation site of tyrosine 125 (E-A-Y(p)-E-M) derived from human alpha Synuclein.

Purification

Purified by antigen-affinity chromatography. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

synuclein alpha , NACP , PARK1 , PARK4 , PD1

Cellular Localization

Cytoplasm,Membrane,Nucleus,Cell junction, synapse,Secreted

Background

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]

Database

Research Area

DATA IMAGES

Anti-alpha Synuclein (phospho Tyr125) antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX50284

GTX50284 ICC/IF Image

ICC/IF analysis of methanol-fixed HeLa cells using GTX50284 alpha Synuclein (phospho Tyr125) antibody.

Anti-alpha Synuclein (phospho Tyr125) antibody used in Western Blot (WB). GTX50284

GTX50284 WB Image

WB analysis of extracts from C2C12 cells untreated or treated with Anisomycin using GTX50284 alpha Synuclein (phospho Tyr125) antibody.

REFERENCE

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REVIEW

There are currently no reviews for alpha Synuclein (phospho Tyr125) antibody (GTX50284). Be the first to share your experience with this product.
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 319