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b-Myb antibody, N-term

Anti-b-Myb antibody, N-term used in Western Blot (WB). GTX77893
Anti-b-Myb antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX77893

Cat. No. GTX77893

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human
Package
50 μg ($419)
See all b-Myb products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.2-2.5 ug/ml
ICC/IF Assay dependent
IHC-P 2-10 ug/ml
Not tested in other applications.

Calculated MW

79 kDa. ( Note )

Positive Control

HepG2

PROPERTIES

Form

Liquid

Buffer

PBS, 2% Sucrose

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a N-terminal region of Human b-Myb.

Purification

Affinity Purified

Conjugation

Unconjugated

RRID

AB_424841

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

MYB proto-oncogene like 2 , B-MYB , BMYB

Cellular Localization

Nucleus

Background

The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]

Database

Research Area

DATA IMAGES

Anti-b-Myb antibody, N-term used in Western Blot (WB). GTX77893

GTX77893 WB Image

WB analysis of HepG2 cells using GTX77893 MYBL2 antibody at 0.2-1μg/ml.

Anti-b-Myb antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX77893

GTX77893 IHC-P Image

IHC-P analysis of human spermatophore tissue using GTX77893 MYBL2 antibody at 4.0-8.0μg/ml.

REFERENCE

Application Reference

Patel AJ et al. Proc Natl Acad Sci U S A 2019; 116 (43) : 21715-21726 Molecular profiling predicts meningioma recurrence and reveals loss of DREAM complex repression in aggressive tumors.
Parisi F et al. Breast Cancer Res 2010; 12 (5) : R66 Benefits of biomarker selection and clinico-pathological covariate inclusion in breast cancer prognostic models.
Application : ICC/IF
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 419