beta 1 Adrenergic Receptor antibody, Internal

Cat. No. GTX89376

Host	Goat
Clonality	Polyclonal
Isotype	IgG
Application	ICC/IF, IHC-P
Reactivity	Human
Package	100 μg ($399)

See all beta 1 Adrenergic Receptor products

Datasheet
Document

View product citations for antibody GTX89376 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
ICC/IF	Assay dependent
IHC-P	Assay dependent

Not tested in other applications.

Calculated MW

51 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX89376-PEP).

Predict Reactivity

Mouse, Rat, Dog(>80% identity)

PROPERTIES

Form

Liquid

Buffer

TBS, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence ESDEARRCYNDPK, from the internal region of the protein sequence according to NP_000675.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

adrenoceptor beta 1 , ADRB1R , B1AR , BETA1AR , RHR

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Jul 2008]

Database

Gene ID: 153 ADRB1
UniProt: P08588 ADRB1

Research Area

DATA IMAGES

GTX89376 IHC-P Image

IHC-P analysis of human heart tissue using GTX89376 beta 1 Adrenergic Receptor antibody, Internal.
Antigen retrieval : Heat induced antigen retrieval with citrate buffer pH 6

GTX89376 ICC/IF Image

ICC/IF analysis of PFA-fixed HeLa cells using GTX89376 beta 1 Adrenergic Receptor antibody, Internal.
Green : Primary antibody
Blue : DAPI
Permeabilization : 0.15% Triton
Dilution : 10μg/ml

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf

Package

List Price ($)

100 μg

$ 399

Qty