GeneTex
United States (US)

beta Amyloid (1-40) antibody [BDI350]

GTX40068_6_WB_18121410_618.jpg

Cat No. GTX40068

Host Mouse
Clonality Monoclonal
Clone Name BDI350
Isotype IgG1
Application WB, ICC/IF, ELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 μg/ml
ICC/IF 1-10 μg/ml
ELISA 0.1 μg/ml
Not tested in other applications.

Calculated MW

87 kDa. ( Note )

Specificity/Sensitivity

Specifically reacts with the C-terminus of Human beta Amyloid 1-40. Does not cross-react with betaAmyloid 1-42.
PROPERTIES

Form

Liquid

Buffer

2X PBS, PEG, Sucrose, 0.09% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.10 mg/ml (Please refer to the vial label for the specific concentration.)

Immunogen

C-terminal peptide conjugated to KLH.

Purification

Purified by thiophilic adsorption and size exclusion chromatography
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Amyloid Beta Precursor Protein,Aaa,Abeta,Abpp,Ad1,Appi,Ctfgamma,Cvap,Pn-Ii,Pn2,Prea4,App

Cellular Localization

Type I membrane protein.

Background

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]

Database

Research Area

DATA IMAGES
GTX40068_6_WB_18121410_618.jpg

GTX40068 WB Image

WB analysis of Amyloid beta A4 peptides using GTX40068 beta Amyloid (1-40) antibody [BDI350] at 2 μg/mL.
Lane 1: Amyloid beta A4 (1-40)
Lane 2: Amyloid beta A4 (1-42)
Lane 3: Amyloid beta A4 (1-43)

Package List Price ($)
$ 329