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beta Arrestin 1 antibody [1H4-F5-C11]

Anti-beta Arrestin 1 antibody [1H4-F5-C11] used in Western Blot (WB). GTX49168

Cat No. GTX49168

Host Mouse
Clonality Monoclonal
Clone Name 1H4-F5-C11
Isotype IgG2b
Application WB
Reactivity Human, Mouse, Rat
Package
100μg ($319)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
Not tested in other applications.

Calculated MW

50 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine(pH 7.4,150 mM NaCl)with 0.02% sodium azide,0.1mg/mlBSA and 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant human ARRB1 protein fragments expressed in E.coli.

Purification

Affinity purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Arrestin Beta 1,Arb1,Arr1,Arrb1

Cellular Localization

Cytoplasm. Nucleus. Cell membrane. Membrane > clathrin-coated pit. Cell projection > pseudopodium. Cytoplasmic vesicle.

Background

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones,neurotransmitters, or sensory signals.Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors.Besides the central nervous system,it is expressed at high levels in peripheral blood leukocytes,and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions.Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.[provided by RefSeq,Jan 2011]

Database

Research Area

DATA IMAGES
Anti-beta Arrestin 1 antibody [1H4-F5-C11] used in Western Blot (WB). GTX49168

GTX49168 WB Image

WB analysis of mouse brain, Raw264.7, MCF7 and PC12 lysates using beta Arrestin 1 antibody at a dilution of 1:500.

REFERENCE
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REVIEW
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Package List Price ($)
$ 319