GeneTex
United States (US)

beta Arrestin 1 antibody

GTX30065_20180530_WB_18121410_347.jpg
GTX30065_20180530_IP_18121410_915.jpg
GTX30065_20180530_ICCIF_18121410_717.jpg

Cat No. GTX30065

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IP
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:20 - 1:100
IP Assay dependent
Not tested in other applications.

Calculated MW

47 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 169-418 of human ARRB1 (NP_004032.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Arrestin Beta 1,Arb1,Arr1,Arrb1

Background

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011]

Database

Research Area

DATA IMAGES
GTX30065_20180530_WB_18121410_347.jpg

GTX30065 WB Image

WB analysis of various samples using GTX30065 beta Arrestin 1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX30065_20180530_IP_18121410_915.jpg

GTX30065 IP Image

IP analysis of K562 cell lysate using GTX30065 beta Arrestin 1 antibody.
IP reaction : 3μg antibody / 200μg cell lysate
Dilution : 1:1000

GTX30065_20180530_ICCIF_18121410_717.jpg

GTX30065 ICC/IF Image

ICC/IF analysis of HeLa cell using GTX30065 beta Arrestin 1 antibody.
Blue : DAPI

Package List Price ($)
$ 319