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beta Catenin antibody, Internal

Anti-beta Catenin antibody, Internal used in ChIP assay (ChIP assay). GTX10342
Anti-beta Catenin antibody, Internal used in Western Blot (WB). GTX10342
Anti-beta Catenin antibody, Internal used in Western Blot (WB). GTX10342
Anti-beta Catenin antibody, Internal used in ChIP assay (ChIP assay). GTX10342

Cat No. GTX10342

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ChIP assay
Reactivity Human
Package
50 μg ($329)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.2-2.5 ug/ml
ChIP assay Assay dependent
Not tested in other applications.

Calculated MW

85 kDa. ( Note )

Positive Control

HCT116 , human fetal heart
PROPERTIES

Form

Liquid

Buffer

1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to an Internal region of Human beta Catenin.

Purification

Affinity Purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

catenin beta 1 , CTNNB , EVR7 , MRD19 , armadillo

Cellular Localization

Cytoplasm,Nucleus,Cytoplasm, cytoskeleton,Cell junction,Cell membrane,Cell junction, synapse

Background

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]

Database

Research Area

DATA IMAGES
Anti-beta Catenin antibody, Internal used in ChIP assay (ChIP assay). GTX10342

GTX10342 ChIP assay Image

ChIP analysis of HCT116 cells using GTX10342 CTNNB1 antibody. Cells were prepared using the Farnham ChIP protocol. Use 2μg antibody GTX10342 CTNNB1 antibody for ChIP assay.

Anti-beta Catenin antibody, Internal used in Western Blot (WB). GTX10342

GTX10342 WB Image

WB analysis of HCT116 cells using GTX10342 CTNNB1 antibody at 1:1000.

Anti-beta Catenin antibody, Internal used in Western Blot (WB). GTX10342

GTX10342 WB Image

WB analysis of human fetal heart tissue using GTX10342 CTNNB1 antibody at 0.2-1μg/ml.

Anti-beta Catenin antibody, Internal used in ChIP assay (ChIP assay). GTX10342

GTX10342 ChIP assay Image

ChIP analysis of HCT116 cells using GTX10342 CTNNB1 antibody. Cells were prepared using the Farnham ChIP protocol. Use 2μg antibody GTX10342 CTNNB1 antibody for ChIP assay.

REFERENCE
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Package List Price ($)
$ 329