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beta Endorphin antibody [B31.15]

Anti-beta Endorphin antibody [B31.15] used in IHC (Frozen sections) (IHC-Fr). GTX21419

Cat No. GTX21419

Host Mouse
Clonality Monoclonal
Clone Name B31.15
Isotype IgG1
Application ICC/IF, IHC-Fr
Reactivity Human
Package
100 μg ($319)
APPLICATION

Application Note

IF: Use at an assay dependant concentration. IHC-Fr: Use at an assay dependant concentration. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

29 kDa. ( Note )

Positive Control

Pituitary gland
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline pH 7.4 containing 15mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full length native protein (purified) (Human).

Purification

>95% by SDS-PAGE
Purified from hybridoma culture supernatant by protein A-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Proopiomelanocortin,Acth,Clip,Lph,Msh,Npp,Obairh,Poc,Pomc

Background

This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endo

Database

Research Area

DATA IMAGES
Anti-beta Endorphin antibody [B31.15] used in IHC (Frozen sections) (IHC-Fr). GTX21419

GTX21419 IHC-Fr Image

Immunohistochemistry staining of human pituitary gland (frozen sections) with anti-human beta Endorphin (GTX21419).

REFERENCE
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REVIEW
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Package List Price ($)
$ 319