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c-Fos antibody

Anti-c-Fos antibody used in Western Blot (WB). GTX27963

Cat. No. GTX27963

Reference 3

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, IP, IHC

Reactivity

 Human, Mouse, Rat
Package
1 ml ($399)
See all c-Fos products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:200
IHC-P Assay dependent
IP Assay dependent
IHC Assay dependent
Not tested in other applications.

Calculated MW

41 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX27997).

PROPERTIES

Form

Liquid

Buffer

PBS, 0.2% Gelatin

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide mapping to the amino terminus of human c-Fos.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_369384

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Fos proto-oncogene, AP-1 transcription factor subunit , AP-1 , C-FOS , p55

Cellular Localization

Nucleus , Endoplasmic reticulum , Cytoplasm, cytosol

Background

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-c-Fos antibody used in Western Blot (WB). GTX27963

GTX27963 WB Image

WB analysis of A431 (A) and HeLa (B) whole cell lysates using GTX27963 c-Fos antibody.

REFERENCE

Application Reference

Turan Y?cel N et al. Biomedicines 2023; 11 (4) Catecholaminergic and Cholinergic Systems Mediate Beneficial Effect of Vortioxetine on Diabetes-Induced Neuropathic Pain.
Yajima H et al. Neurobiology of Aging 2018; 64 : 139-146 Early-life-stress induces cognitive disorder in middle-aged mice.
Application : IHC-P
Reactivity : Mouse
Trollmann R et al. Am J Physiol Regul Integr Comp Physiol 2010; 299 (6) : R1489-99 Late-gestational systemic hypoxia leads to a similar early gene response in mouse placenta and developing brain.
Application : IHC-P
Reactivity : Mouse
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Package List Price ($)
$ 399