GeneTex
United States (US)

c-Fos (phospho Ser362) antibody

GTX32391_20190131_WB_19013102_669.jpg
GTX32391_20190131_IHC-P_19013102_302.jpg

Cat No. GTX32391

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
IHC-P 1:100 - 1:200
Not tested in other applications.

Calculated MW

41 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

0.42% Potassium phosphate, 0.87% Sodium chloride pH 7.3, 30% glycerol, 0.01% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of c-Fos. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Fos Proto-Oncogene, Ap-1 Transcription Factor Subunit,Ap-1,C-Fos,P55,Fos

Cellular Localization

Cytoplasm,Cytosol,Endoplasmic reticulum,Nucleus

Background

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX32391_20190131_WB_19013102_669.jpg

GTX32391 WB Image

WB analysis of HepG2 (A), Adriamycin-treated HeLa (B) whole cell lysates using GTX32391 c-Fos (phospho Ser362) antibody.

GTX32391_20190131_IHC-P_19013102_302.jpg

GTX32391 IHC-P Image

IHC-P analysis of formalin fixed human lung cancer tissue section using GTX32391 c-Fos (phospho Ser362) antibody.
Antigen retrieval : Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0)

Package List Price ($)
$ 319