*Optimal dilutions/concentrations should be determined by the researcher.
|20 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension
Not tested in other applications.
The mouse monoclonal antibody 104D2 detects extracellular part of CD117 / c-Kit protooncogen.
PBS, 15mM sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Batch dependent (Please refer to the vial label for the specific concentration.)
MOLM-1 megakaryocytic cells
Purified by size-exclusion chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
CD117 , CKit , KIT , KIT protooncogene receptor tyrosine kinase , PBT , SCFR , c-Kit , KIT proto-oncogene, receptor tyrosine kinase
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]