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c-Kit antibody [104D2]

Cat. No. GTX00465

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 104D2

Isotype

 IgG1

Application

 ICC/IF, IHC-Fr, FACS, IP

Reactivity

 Human, Bovine, Primate
Package
100 μg ($339)
See all c-Kit products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IHC-Fr Assay dependent
FACS Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

110 kDa. ( Note )

Product Note

The mouse monoclonal antibody 104D2 detects extracellular part of CD117 / c-Kit protooncogen.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

MOLM-1 megakaryocytic cells

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD117 , CKit , KIT , KIT protooncogene receptor tyrosine kinase , PBT , SCFR , c-Kit , KIT proto-oncogene, receptor tyrosine kinase

Cellular Localization

Cell membrane,Cytoplasm

Background

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339