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c-Kit antibody [C117/370]

Anti-c-Kit antibody [C117/370] used in IHC (Paraffin sections) (IHC-P). GTX34606
Anti-c-Kit antibody [C117/370] used in IHC (Paraffin sections) (IHC-P). GTX34606

Cat. No. GTX34606

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 C117/370

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
100 μg ($529)
See all c-Kit products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1-2μg/ml for 30 minutes at RT

Note :

IHC-P
Staining of formalin-fixed tissues require heating tissue sections in 1mM EDTA buffer, pH 9.5, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

110 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human CD117 protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD117 , CKit , KIT , KIT protooncogene receptor tyrosine kinase , PBT , SCFR , c-Kit , KIT proto-oncogene, receptor tyrosine kinase

Cellular Localization

Cell membrane,Cytoplasm

Background

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-c-Kit antibody [C117/370] used in IHC (Paraffin sections) (IHC-P). GTX34606

GTX34606 IHC-P Image

IHC-P analysis of human gastrointestinal stromal tumor (GIST) tissue using GTX34606 c-Kit antibody [C117/370].

Anti-c-Kit antibody [C117/370] used in IHC (Paraffin sections) (IHC-P). GTX34606

GTX34606 IHC-P Image

IHC-P analysis of human gastrointestinal stromal tumor (GIST) tissue using GTX34606 c-Kit antibody [C117/370].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529