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c-Kit (phospho Tyr568/Tyr570) antibody

Orthogonal
Anti-c-Kit (phospho Tyr568/Tyr570) antibody used in Western Blot (WB). GTX25616
Anti-c-Kit (phospho Tyr568/Tyr570) antibody used in Western Blot (WB). GTX25616

Cat. No. GTX25616

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse, Rat
Package
50 μl ($399)
See all c-Kit products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:2000
Not tested in other applications.

Calculated MW

110 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA, 50% Glycerol

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human c-Kit that contains tyrosines 568 and 570. The sequence is conserved in mouse, rat, chicken, cow and dog.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_380598

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

KIT proto-oncogene, receptor tyrosine kinase , C-Kit , CD117 , MASTC , PBT , SCFR

Background

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-c-Kit (phospho Tyr568/Tyr570) antibody used in Western Blot (WB). GTX25616

GTX25616 WB Image

WB analysis of 20 μg of A549 (Lane1) and serum starved A549 (Lane2) cell lysate using GTX25616 c-Kit (phospho Tyr568/Tyr570) antibody.
Dilution : 1:1000

Anti-c-Kit (phospho Tyr568/Tyr570) antibody used in Western Blot (WB). GTX25616

GTX25616 WB Image

Orthogonal

WB analysis of M07e cells left untreated (Lane 1) or treated (Lane 2-5) with SCF using GTX25616 c-Kit (phospho Tyr568/Tyr570) antibody.

REFERENCE

Application Reference

Jeong YM et al. Stem Cells Int 2020; 2020 : 1835950 Substance P Administered after Myocardial Infarction Upregulates Microphthalmia-Associated Transcription Factor, GATA4, and the Expansion of c-Kit+ Cells.
Application : WB
Reactivity : Rat
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399