GeneTex
United States (US)

c-Myb (aa557-569) antibody, Internal

GTX88080_2528_WB_18121411_964.jpg

Cat No. GTX88080

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.5-1.5μg/ml
Not tested in other applications.

Calculated MW

72 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88080-PEP).

Specificity/Sensitivity

This antibody is expected to recognize all reported isofoms. (NP_001123645.1; NP_005366.2; NP_001123644.1; NP_001155128.1; NP_001155129.1; NP_001155130.1; NP_001155131.1; NP_001155132.1).

Predict Reactivity

Mouse, Rat, Bovine, Dog, Pig(>80% identity)
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-HRDQTVKTQKENT, from the internal region of the protein sequence according to NP_001123645.1; NP_005366.2; NP_001123644.1; NP_001155128.1; NP_001155129.1; NP_001155130.1; NP_001155131.1; NP_001155132.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Myb Proto-Oncogene, Transcription Factor,Cmyb,C-Myb,C-Myb_Cds,Efg,Myb

Background

This gene encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009]

Database

Research Area

DATA IMAGES
GTX88080_2528_WB_18121411_964.jpg

GTX88080 WB Image

WB analysis of Jurkat lysate using GTX88080 c-Myb (aa557-569) antibody, Internal.
Dilution : 0.5µg/ml
Loading : 35µg protein in RIPA buffer