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c-Myc antibody [GT1265]

KO/KD
Anti-c-Myc antibody [GT1265] used in Western Blot (WB). GTX02877
Anti-c-Myc antibody [GT1265] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX02877
Anti-c-Myc antibody [GT1265] used in Western Blot (WB). GTX02877
Anti-c-Myc antibody [GT1265] used in Western Blot (WB). GTX02877

Cat. No. GTX02877

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 GT1265

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all c-Myc products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
Not tested in other applications.

Calculated MW

49 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human c-Myc

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

MRTL,MYCC,c-Myc,bHLHe39

Cellular Localization

Nucleoplasm,Nucleolus

Background

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-c-Myc antibody [GT1265] used in Western Blot (WB). GTX02877

GTX02877 WB Image

WB analysis of mouse ovary tissue lysate using GTX02877 c-Myc antibody [GT1265].
Dilution : 1:1000
Loading : 25μg per lane

Anti-c-Myc antibody [GT1265] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX02877

GTX02877 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX02877 c-Myc antibody [GT1265].
Red : Primary antibody
Blue : DAPI
Dilution : 1:100

Anti-c-Myc antibody [GT1265] used in Western Blot (WB). GTX02877

GTX02877 WB Image

WB analysis of various cell lysates using GTX02877 c-Myc antibody [GT1265].
Dilution : 1:1000
Loading : 25μg per lane

Anti-c-Myc antibody [GT1265] used in Western Blot (WB). GTX02877

GTX02877 WB Image

KO/KD

WB analysis of extracts from normal (control) and c-Myc knockout (KO) HCT116 cells using GTX02877 c-Myc antibody [GT1265].
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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Package List Price ($)
$ 399