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c-Myc antibody (HRP)

Anti-c-Myc antibody (HRP) used in Western Blot (WB). GTX12213

Cat. No. GTX12213

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, ELISA, IHC

Reactivity

 Human
Package
50 μg ($399)
See all c-Myc products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1,000 - 1:30,000
ICC/IF 1:200-1:500
ELISA 1:10,000-1:100,000
IHC Assay dependent
Not tested in other applications.

Calculated MW

49 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.2% BSA

Preservative

0.1% ProClin 400

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide corresponding to aa 410-419 (EQKLISEEDL) of human myc conjugated to KLH.

Purification

Purified by affinity chromatography

Conjugation

Horseradish peroxidase(HRP)
Ratio : 4 HRP molecules per IgG molecule.

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

MRTL , MYC , MYCC , bHLHe39 , cMyc , vmyc avian myelocytomatosis viral oncogene homolog , cmyc , MYC proto-oncogene, bHLH transcription factor

Cellular Localization

Nucleus,Nucleoplasm,Nucleolus

Background

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-c-Myc antibody (HRP) used in Western Blot (WB). GTX12213

GTX12213 WB Image

WB analysis of E. coli expressing a multi-tag fusion protein using GTX12213 c-Myc antibody (HRP).
Dilution : 0.04μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399