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delta Sarcoglycan antibody [δSarc3/12C1]

Cat. No. GTX01943

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 δSarc3/12C1

Isotype

 IgG2a

Application

 IHC-Fr

Reactivity

 Human
Package
500 μl ($719)
See all delta Sarcoglycan products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-Fr 1:25–1:50

Note :

IHC-Fr
Freeze specimen tissue blocks in isopentane chilled in liquid nitrogen.
Not tested in other applications.

Calculated MW

32 kDa. ( Note )

Product Note

We do not recommend use of this product for Mouse,Rat,Rabbit,Dog,Hamster,Chicken,Pig samples.

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Synthetic peptide containing amino acids 1-19 at the N-terminus of the human delta-sarcoglycan sequence (Jung D. et al.,1966).

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

sarcoglycan delta , 35DAG , CMD1L , DAGD , LGMDR6 , SG-delta , SGCDP , SGD

Cellular Localization

Cytoplasm, cytoskeleton

Background

The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

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REVIEW

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Package List Price ($)
$ 719