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gamma Sarcoglycan antibody

Anti-gamma Sarcoglycan antibody used in Western Blot (WB). GTX117176
Anti-gamma Sarcoglycan antibody used in Western Blot (WB). GTX117176

Cat No. GTX117176

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Mouse, Rat
Package
100 μl ($379),
25 μl ($169)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

32 kDa. ( Note )

Positive Control

mouse muscle , rat muscle

Predict Reactivity

Human, Rabbit, Bovine, Dog(>80% identity)

PROPERTIES

Form

Liquid

Buffer

1XPBS (pH7), 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human gamma Sarcoglycan. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2885415

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

sarcoglycan gamma , 35DAG , A4 , DAGA4 , DMDA , DMDA1 , LGMD2C , LGMDR5 , MAM , SCARMD2 , SCG3 , gamma-SG

Cellular Localization

Cell membrane , sarcolemma; Single-pass type II membrane protein , Cytoplasm , cytoskeleton

Background

This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008]

Database

Research Area

DATA IMAGES

Anti-gamma Sarcoglycan antibody used in Western Blot (WB). GTX117176

GTX117176 WB Image

Gamma Sarcoglycan antibody detects Gamma Sarcoglycan protein by western blot analysis. Rat tissue extracts (50 μg) was separated by 12 % SDS-PAGE, and the membrane was blotted with Gamma Sarcoglycan antibody (GTX117176) diluted by 1:1000.

Anti-gamma Sarcoglycan antibody used in Western Blot (WB). GTX117176

GTX117176 WB Image

Gamma Sarcoglycan antibody detects Gamma Sarcoglycan protein by western blot analysis. Mouse tissue extracts (50 μg) was separated by 12 % SDS-PAGE, and the membrane was blotted with Gamma Sarcoglycan antibody (GTX117176) diluted by 1:1000.

REFERENCE

REVIEW

gamma Sarcoglycan antibody Cat No. GTX117176

Rating ( Average 5 based on 2 users reviews)
Application
Western Blot(WB) ( Average 5 based on 1 users reviews)
IHC (Paraffin sections)(IHC-P) ( Average 5 based on 1 users reviews)
Date : Anonymous submitted on 10-Aug-2021
Score :
Application Tested : WB
Sample Species : Ms
Figure Note : The data was peer reviewed and published in the journal Int J Mol Sci in 2019.PMID: 31689918
Date : Anonymous submitted on 10-Aug-2021
Score :
Application Tested : IHC-P
Sample Species : Ms
Figure Note : The data was peer reviewed and published in the journal Int J Mol Sci in 2019.PMID: 31689918
SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 379
$ 169