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hCG alpha antibody [SPM552]

Anti-hCG alpha antibody [SPM552] used in IHC (Paraffin sections) (IHC-P). GTX34775

Cat No. GTX34775

Host Mouse
Clonality Monoclonal
Clone Name SPM552
Isotype IgG1
Application IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1-2ug/ml for 30 minutes at RT
Not tested in other applications.

Calculated MW

13 kDa. ( Note )

Specificity/Sensitivity

This MAb reacts with a protein of ~13kDa, identified as α sub-unit of HCG. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the ? and ? subunits. The ? subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH).
PROPERTIES

Form

Liquid

Buffer

Prepared in 10mM PBS with 0.05% BSA and 0.05% azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Immunogen

Recombinant hCG alpha protein

Purification

Ab purified from Bioreactor Concentrate by Protein A/G

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Glycoprotein Hormones, Alpha Polypeptide,Cg-Alpha,Fsha,Gpha1,Gpha,Hcg,Lha,Tsha,Cga

Background

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Database

Research Area

DATA IMAGES
Anti-hCG alpha antibody [SPM552] used in IHC (Paraffin sections) (IHC-P). GTX34775

GTX34775 IHC-P Image

Formalin-fixed, paraffin-embedded human Placenta stained with hCG alpha Monoclonal Antibody (SPM552).

Package List Price ($)
$ 329