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hCG beta antibody [INN-hCG-68]

Cat. No. GTX11391

Reference 3

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 INN-hCG-68

Isotype

 IgG1

Application

 WB, IP, ELISA, RIA

Reactivity

 Human
Package
250 μg ($399)
See all hCG beta products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IP Assay dependent
ELISA 1/1000-1/80,000
RIA Assay dependent
Not tested in other applications.

Product Note

This antibody recognizes the beta 7 epitope on hCG beta. It recognises free human chorionic gonadotrophin beta (hCG beta), but does not bind to holo-hGG, holo-hLH or free hLH beta.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full-length mature hCG

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_369407

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CGB8 Antibody , CGB7 Antibody , CGB Antibody , CGB5 Antibody , HCGB Antibody , CGB3 Antibody

Background

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]

Research Area

REFERENCE

Application Reference

Butch AW et al. Drug Test Anal 2017; (Epub) urine reference intervals for human chorionic * (hcg) isoforms by immunoextraction-tandem mass spectrometry to detect hcg use.
Application : IP
Reactivity : Human
Woldemariam GA et al. Clin Chem 2014; (Epub) immunoextraction-tandem mass spectrometry method for measuring intact human chorionic *, free β-subunit, and β-subunit core fragment in urine.
Application : IP
Reactivity : Human

Clone Reference

Ben-Menahem D et al. J Biol Chem 2001; 276 (32):29871-9 the position of the alpha and beta subunits in a single chain variant of human chorionic * affects the heterodimeric interaction of the subunits and receptor-binding epitopes.
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399