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hnRNP A2B1 antibody [DP3B3]

Cat. No. GTX26102

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 DP3B3

Isotype

 IgG2a

Application

 WB, ICC/IF, IP, ELISA, IHC

Reactivity

 Human, Mouse, Chicken
Package
50 μl ($399)
See all hnRNP A2B1 products

APPLICATION

Application Note

Recommended Starting Dilutions:
1:500 for western blot
Optimal dilutions should be determined experimentally by the researcher.

Calculated MW

37 kDa. ( Note )

Product Note

Human (& chicken) hnRNP A2B1. Cross reacts with mouse for IHC on lung tissue. Reacts predominantly with a 36 kDa band (A2), & a 38kDa band (B1)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Bacterially expressed His-hnRNP-A2 fusion protein (Human)

Purification

Protein A

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

heterogeneous nuclear ribonucleoprotein A2/B1 , HNRNPA2 , HNRNPB1 , HNRPA2 , HNRPA2B1 , HNRPB1 , IBMPFD2 , RNPA2 , SNRPB1

Cellular Localization

nucleoplasm , Cytoplasm

Background

This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. [provided by RefSeq, Jul 2008]

Database

  • Gene ID: 3181 HNRNPA2B1
  • UniProt: P22626 HNRNPA2B1

Research Area

REFERENCE

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399