GeneTex

  • Country / Location Selection

United States (US)

hnRNP C1/C2 antibody [4F4]

Cat. No. GTX10294

Reference 2

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 4F4

Isotype

 IgG1

Application

 WB, ICC/IF, IP, ELISA

Reactivity

 Human, Hamster, Chicken, Monkey
Package
50 μl ($279)
See all hnRNP C1/C2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.1-0.2 μg/ml
ICC/IF Assay dependent
IP Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

34 kDa. ( Note )

Positive Control

HeLa nuclear extract

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

RNPs eluted from oligo (dT) cellulose column.

Purification

Purified immunoglobulin

Conjugation

Unconjugated

RRID

AB_368711

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

heterogeneous nuclear ribonucleoprotein C (C1/C2) , C1 , C2 , HNRNP , HNRPC , SNRPC

Cellular Localization

Nucleus

Background

The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. hnRNP C1 and C2 are encoded by one gene; the two alternatively spliced transcript variants have been described.

Database

Research Area

REFERENCE

Application Reference

Nagel M et al. RNA 2022; 29 (1) : 55-68 The kinesin motor KIF1C is a putative transporter of the exon junction complex in neuronal cells.
Claudio Asencio et al. Life Science Alliance 2018; (Epub) Silica-based solid-phase extraction of cross-linked nucleic acid–bound proteins.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

There are currently no reviews for hnRNP C1/C2 antibody [4F4] (GTX10294). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 279