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hnRNP F antibody [3H4]

Cat. No. GTX26095

Reference 2

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 3H4

Isotype

 IgG1

Application

 WB, ELISA

Reactivity

 Human
Package
50 μl ($399)
See all hnRNP F products

APPLICATION

Application Note

Recommended Starting Dilutions:
For WB: Use at 1:500
Optimal dilutions should be determined experimentally by the researcher.

Calculated MW

46 kDa. ( Note )

Product Note

Human hnRNP-F. Reacts with a band in the region of 47-50kDa. Cross Reactivity undeterminined

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full length hnRNP F protein (human)

Purification

Protein A

Conjugation

Unconjugated

RRID

AB_371617

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

heterogeneous nuclear ribonucleoprotein F , HNRPF , OK/SW-cl.23 , mcs94-1

Cellular Localization

nucleoplasm

Background

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

Application Reference

Ajiro M et al. J Virol 2016; SRSF3 and hnRNP A1 regulate alternative RNA splicing and gene expression of human papillomavirus type 18 through two functionally distinguishable cis-elements.
Application : WB
Reactivity : Human
Lefave CV et al. EMBO J 2011; 30 (19) : 4084-97 Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas.
Application : WB
Reactivity : Human
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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399