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hnRNP L antibody

Anti-hnRNP L antibody used in Western Blot (WB). GTX87723
Anti-hnRNP L antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX87723
Anti-hnRNP L antibody used in IHC (Paraffin sections) (IHC-P). GTX87723

Cat No. GTX87723

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, IHC-P

Reactivity

Human
Package
100 μg ($359)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500~1:1000
ICC/IF 1:100~1:500
IHC-P 1:50~1:100
Not tested in other applications.

Calculated MW

64 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH 7.4, 150mM NaCl, 0.02% sodium azide, 50% glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human hnRNP L (61-110).

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

HNRNPL , HNRPL , P/OKcl.14 , heterogeneous nuclear ribonucleoprotein L , hnRNPL , hnRNP L

Cellular Localization

Nucleus,Nucleoplasm,Cytoplasm

Background

Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-hnRNP L antibody used in Western Blot (WB). GTX87723

GTX87723 WB Image

WB analysis of HeLa, Jurkat, and HUVEC cell lysates using GTX87723 hnRNP L antibody. The lane on the right is blocked with the synthesized peptide.

Anti-hnRNP L antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX87723

GTX87723 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX87723 hnRNP L antibody. The picture on the right is blocked with the synthesized peptide.

Anti-hnRNP L antibody used in IHC (Paraffin sections) (IHC-P). GTX87723

GTX87723 IHC-P Image

IHC-P analysis of human colon carcinoma tissue using GTX87723 hnRNP L antibody. The picture on the right is blocked with the synthesized peptide.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 359