APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500~1:1000 |
| 1:100~1:500 |
| 1:50~1:100 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human hnRNP L (61-110).
Purification
Purified by antigen-affinity chromatography
From serum
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
HNRNPL , HNRPL , P/OKcl.14 , heterogeneous nuclear ribonucleoprotein L , hnRNPL , hnRNP L
Cellular Localization
Nucleus,Nucleoplasm,Cytoplasm
Background
Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX87723 ICC/IF Image
ICC/IF analysis of HeLa cells using GTX87723 hnRNP L antibody. The picture on the right is blocked with the synthesized peptide.
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GTX87723 IHC-P Image
IHC-P analysis of human colon carcinoma tissue using GTX87723 hnRNP L antibody. The picture on the right is blocked with the synthesized peptide.
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GTX87723 WB Image
WB analysis of HeLa, Jurkat, and HUVEC cell lysates using GTX87723 hnRNP L antibody. The lane on the right is blocked with the synthesized peptide.
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REFERENCE
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REVIEW
There are currently no reviews for hnRNP L antibody (GTX87723). Be the first to share your experience with this product.
