*Optimal dilutions/concentrations should be determined by the researcher.
|4 - 8 μg/ml
Not tested in other applications.
Mouse, Rat, Rabbit, Sheep, Bovine, Dog, Hamster, Guinea pig, Pig, Bat, Chimpanzee, Elephant, Gibbon, Gorilla, Marmoset, Opossum, Orangutan, Panda(>80% identity)
PBS, 0.1% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human CHRM2.
Purified by affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
cholinergic receptor muscarinic 2 , CHRM2 , HM2 , mAChR M2 , Muscarinic Acetylcholine Receptor 2
Cell membrane,Cell junction,Synapse,Postsynaptic cell membrane
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]
GTX71168 IHC-P Image
IHC-P analysis of human brain, neurons and glia tissue using GTX71168 mAChR M2 antibody.
Antigen retrieval : Heat-induced antigen retrieval