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mAChR M2 antibody

Anti-mAChR M2 antibody used in IHC (Paraffin sections) (IHC-P). GTX71171
Anti-mAChR M2 antibody used in IHC (Paraffin sections) (IHC-P). GTX71171
Anti-mAChR M2 antibody used in IHC (Paraffin sections) (IHC-P). GTX71171
Anti-mAChR M2 antibody used in IHC (Paraffin sections) (IHC-P). GTX71171
Anti-mAChR M2 antibody used in IHC (Paraffin sections) (IHC-P). GTX71171
Anti-mAChR M2 antibody used in IHC (Paraffin sections) (IHC-P). GTX71171
Anti-mAChR M2 antibody used in IHC (Paraffin sections) (IHC-P). GTX71171

Cat No. GTX71171

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P

Reactivity

Human, Mouse, Rat, Rabbit, Sheep, Bovine, Dog, Hamster, Guinea pig, Pig, Monkey, Horse
Package
25 μg ($269)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 6 - 15 μg/ml
Not tested in other applications.

Calculated MW

52 kDa. ( Note )

Predict Reactivity

Zebrafish, Chicken, Bat, Chimpanzee, Elephant, Gibbon, Gorilla, Marmoset, Opossum, Orangutan, Panda, Turkey, Xenopus, Platypus, Stickleback(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human CHRM2.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

cholinergic receptor muscarinic 2 , CHRM2 , HM2 , mAChR M2 , Muscarinic Acetylcholine Receptor 2

Cellular Localization

Cell membrane,Cell junction,Synapse,Postsynaptic cell membrane

Background

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-mAChR M2 antibody used in IHC (Paraffin sections) (IHC-P). GTX71171

GTX71171 IHC-P Image

IHC-P analysis of brain, amygdala neuron tissue using GTX71171 mAChR M2 antibody.

Anti-mAChR M2 antibody used in IHC (Paraffin sections) (IHC-P). GTX71171

GTX71171 IHC-P Image

IHC-P analysis of brain, hypothalamus tissue using GTX71171 mAChR M2 antibody.

Anti-mAChR M2 antibody used in IHC (Paraffin sections) (IHC-P). GTX71171

GTX71171 IHC-P Image

IHC-P analysis of brain, hypothalamusbrain, glioblastoma tissue using GTX71171 mAChR M2 antibody.

Anti-mAChR M2 antibody used in IHC (Paraffin sections) (IHC-P). GTX71171

GTX71171 IHC-P Image

IHC-P analysis of human brain, glioblastoma tissue using GTX71171 mAChR M2 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-mAChR M2 antibody used in IHC (Paraffin sections) (IHC-P). GTX71171

GTX71171 IHC-P Image

IHC-P analysis of human ovary, carcinoma tissue using GTX71171 mAChR M2 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-mAChR M2 antibody used in IHC (Paraffin sections) (IHC-P). GTX71171

GTX71171 IHC-P Image

IHC-P analysis of human brain, neurons and glia tissue using GTX71171 mAChR M2 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-mAChR M2 antibody used in IHC (Paraffin sections) (IHC-P). GTX71171

GTX71171 IHC-P Image

IHC-P analysis of human lung, small cell carcinoma tissue using GTX71171 mAChR M2 antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf