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mAChR M3 antibody

Anti-mAChR M3 antibody used in IHC (Paraffin sections) (IHC-P). GTX71587
Anti-mAChR M3 antibody used in IHC (Paraffin sections) (IHC-P). GTX71587
Anti-mAChR M3 antibody used in IHC (Paraffin sections) (IHC-P). GTX71587
Anti-mAChR M3 antibody used in IHC (Paraffin sections) (IHC-P). GTX71587
Anti-mAChR M3 antibody used in IHC (Paraffin sections) (IHC-P). GTX71587
Anti-mAChR M3 antibody used in IHC (Paraffin sections) (IHC-P). GTX71587

Cat No. GTX71587

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P

Reactivity

Human, Monkey
Package
25 μg ($269)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 72 μg/ml
Not tested in other applications.

Calculated MW

66 kDa. ( Note )

Predict Reactivity

Mouse, Rat, Rabbit, Sheep, Bovine, Dog, Hamster, Chicken, Guinea pig, Pig, Chimpanzee, Elephant, Gibbon, Gorilla, Horse, Lizard, Opossum, Orangutan, Turkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 19 amino acid peptide from C-terminus of human CHRM3 / M3.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

cholinergic receptor muscarinic 3 , CHRM3 , EGBRS , HM3 , PBS , mAChR M3 , Muscarinic Acetylcholine Receptor 3

Cellular Localization

Cell membrane,Cell junction,Synapse,Postsynaptic cell membrane,Basolateral cell membrane

Background

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016]

Database

Research Area

DATA IMAGES

Anti-mAChR M3 antibody used in IHC (Paraffin sections) (IHC-P). GTX71587

GTX71587 IHC-P Image

IHC-P analysis of brain, alzheimer's disease neurofibrillary tangle tissue using GTX71587 mAChR M3 antibody.

Anti-mAChR M3 antibody used in IHC (Paraffin sections) (IHC-P). GTX71587

GTX71587 IHC-P Image

IHC-P analysis of brain, glioblastoma tissue using GTX71587 mAChR M3 antibody.

Anti-mAChR M3 antibody used in IHC (Paraffin sections) (IHC-P). GTX71587

GTX71587 IHC-P Image

IHC-P analysis of human brain, neurons and glia tissue using GTX71587 mAChR M3 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-mAChR M3 antibody used in IHC (Paraffin sections) (IHC-P). GTX71587

GTX71587 IHC-P Image

IHC-P analysis of human ovary, carcinoma tissue using GTX71587 mAChR M3 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-mAChR M3 antibody used in IHC (Paraffin sections) (IHC-P). GTX71587

GTX71587 IHC-P Image

IHC-P analysis of human brain, glioblastoma tissue using GTX71587 mAChR M3 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-mAChR M3 antibody used in IHC (Paraffin sections) (IHC-P). GTX71587

GTX71587 IHC-P Image

IHC-P analysis of human heart tissue using GTX71587 mAChR M3 antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf