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mAChR M4 antibody

Anti-mAChR M4 antibody used in IHC (Paraffin sections) (IHC-P). GTX71307
Anti-mAChR M4 antibody used in IHC (Paraffin sections) (IHC-P). GTX71307

Cat No. GTX71307

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P

Reactivity

Human, Mouse, Rat, Bovine, Hamster, Guinea pig, Pig, Horse
Package
25 μg ($269)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 10 - 20 μg/ml
Not tested in other applications.

Calculated MW

53 kDa. ( Note )

Predict Reactivity

Dog, Bat, Elephant, Gorilla, Panda(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human CHRM4.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

cholinergic receptor muscarinic 4 , CHRM4 , HM4 , M4R , Muscarinic Acetylcholine Receptor M4 , mAChR M4

Cellular Localization

Cell membrane,Cell junction,Synapse,Postsynaptic cell membrane

Background

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-mAChR M4 antibody used in IHC (Paraffin sections) (IHC-P). GTX71307

GTX71307 IHC-P Image

IHC-P analysis of human brain, neurons and glia tissue using GTX71307 mAChR M4 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-mAChR M4 antibody used in IHC (Paraffin sections) (IHC-P). GTX71307

GTX71307 IHC-P Image

IHC-P analysis of human lymph node, hodgkins lymphoma tissue using GTX71307 mAChR M4 antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf