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mGluR1 antibody

Anti-mGluR1 antibody used in Western Blot (WB). GTX37416
Anti-mGluR1 antibody used in IHC (Paraffin sections) (IHC-P). GTX37416
Anti-mGluR1 antibody used in IHC (Paraffin sections) (IHC-P). GTX37416

Cat. No. GTX37416

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all mGluR1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-2000
IHC-P 1:400-800
Not tested in other applications.

Calculated MW

132 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM TBS, 0.5% BSA, 25% Glycerol

Preservative

0.015% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived between 661-740 amino acids of human GRM1

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

glutamate metabotropic receptor 1 , GPRC1A , MGLU1 , MGLUR1 , PPP1R85 , SCA44 , SCAR13

Cellular Localization

Cell membrane

Background

This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]

Database

Research Area

DATA IMAGES

Anti-mGluR1 antibody used in Western Blot (WB). GTX37416

GTX37416 WB Image

WB analysis of mouse brain lysates (Lane 1) and mouse embryo lysates (Lane 2) using GTX37416 mGluR1 antibody.
Dilution : 1:200

Anti-mGluR1 antibody used in IHC (Paraffin sections) (IHC-P). GTX37416

GTX37416 IHC-P Image

IHC-P analysis of human lung carcinoma tissue using GTX37416 mGluR1 antibody.
Dilution : 1:200

Anti-mGluR1 antibody used in IHC (Paraffin sections) (IHC-P). GTX37416

GTX37416 IHC-P Image

IHC-P analysis of rat brain tissue using GTX37416 mGluR1 antibody.
Dilution : 1:200

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Proclin.pdf
Package List Price ($)
$ 399