GeneTex
United States (US)

mGluR1 antibody

GTX37416_20190129_WB_19012901_473.jpg
GTX37416_20190129_IHC-P_2_19012901_295.jpg
GTX37416_20190129_IHC-P_3_19012901_749.jpg

Cat No. GTX37416

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-2000
IHC-P 1:400-800
Not tested in other applications.

Calculated MW

132 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

0.01M TBS pH7.4, 0.5% BSA, 0.015% ProClin™ 300, 25% glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived between 661-740 amino acids of human GRM1

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Glutamate Metabotropic Receptor 1,Gprc1A,Mglu1,Mglur1,Ppp1R85,Sca44,Scar13,Grm1

Cellular Localization

Cell membrane

Background

This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]

Database

Research Area

DATA IMAGES
GTX37416_20190129_WB_19012901_473.jpg

GTX37416 WB Image

WB analysis of mouse brain lysates (Lane 1) and mouse embryo lysates (Lane 2) using GTX37416 mGluR1 antibody.
Dilution : 1:200

GTX37416_20190129_IHC-P_2_19012901_295.jpg

GTX37416 IHC-P Image

IHC-P analysis of human lung carcinoma tissue using GTX37416 mGluR1 antibody.
Dilution : 1:200

GTX37416_20190129_IHC-P_3_19012901_749.jpg

GTX37416 IHC-P Image

IHC-P analysis of rat brain tissue using GTX37416 mGluR1 antibody.
Dilution : 1:200

Package List Price ($)
$ 339