*Optimal dilutions/concentrations should be determined by the researcher.
|5 - 10 μg/ml
Not tested in other applications.
Mouse, Rat, Rabbit, Bovine, Dog, Hamster, Pig, Monkey, Bat, Chimpanzee, Elephant, Gibbon, Gorilla, Horse, Marmoset, Panda, Platypus(>80% identity)
PBS, 0.1% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Synthetic 19 amino acid peptide from N-terminal extracellular domain of human mGluR2.
Purified by affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
glutamate metabotropic receptor 2 , GLUR2 , GPRC1B , MGLUR2 , mGlu2
Cell membrane; Multi-pass membrane protein,Cell junction, synapse,Cell projection, dendrite
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017]
GTX13192 IHC-P Image
IHC-P analysis of human brain tissue (neurons and glia) using GTX13192 mGluR2 antibody.
Antigen retrival : Heat-induced antigen retrieval