GeneTex
United States (US)

mGluR4 antibody

Anti-mGluR4 antibody used in Western Blot (WB). GTX33978
Anti-mGluR4 antibody used in Western Blot (WB). GTX33978

Cat No. GTX33978

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ELISA, IHC
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ELISA Assay dependent
IHC Assay dependent
Not tested in other applications.

Calculated MW

102 kDa. ( Note )

Specificity/Sensitivity

mGluR-4 Polyclonal Antibody detects endogenous levels of mGluR-4 protein.
PROPERTIES

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Synthesized peptide derived from the C-terminal region of human mGluR-4 at AA range: 820-900.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Glutamate Metabotropic Receptor 4,Gprc1D,Mglur4,Mglu4,Grm4

Background

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

Database

Research Area

DATA IMAGES
Anti-mGluR4 antibody used in Western Blot (WB). GTX33978

GTX33978 WB Image

Western Blot (WB) analysis of specific cells using mGluR-4 Polyclonal Antibody.

Anti-mGluR4 antibody used in Western Blot (WB). GTX33978

GTX33978 WB Image

Western Blot (WB) analysis of 293 cells using mGluR-4 Polyclonal Antibody.

Package List Price ($)
$ 319