APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| Assay dependent |
| 12 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Zebrafish, Catfish, Chimpanzee, Elephant, Gibbon, Gorilla, Horse, Lizard, Marmoset, Opossum, Panda, Pufferfish, Xenopus, Platypus, Sea bass, Stickleback(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 15 amino acid peptide from N-terminal extracellular domain of human GRM6 / MGLUR6.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_375799
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
, CSNB1B , GPRC1F , GRM6 , MGLUR6 , glutamate metabotropic receptor 6 , mGlu6 , mGluR6 , Metabotropic Glutamate Receptor 6
Cellular Localization
Cell membrane,Endoplasmic reticulum membrane,Golgi apparatus membrane,Cell projection,Dendrite
Background
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Mutations in this gene result in congenital stationary night blindness type 1B. [provided by RefSeq, May 2018]
Database
Research Area
DATA IMAGES
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GTX71531 IHC-P Image
IHC-P analysis of eye, retina, ganglion cells tissue using GTX71531 mGluR6 antibody.
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GTX71531 IHC-P Image
IHC-P analysis of human ovary, carcinoma tissue using GTX71531 mGluR6 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX71531 IHC-P Image
IHC-P analysis of human prostate, carcinoma tissue using GTX71531 mGluR6 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX71531 IHC-P Image
IHC-P analysis of human brain, glioblastoma tissue using GTX71531 mGluR6 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX71531 IHC-P Image
IHC-P analysis of eye, retina tissue using GTX71531 mGluR6 antibody.
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GTX71531 IHC-P Image
IHC-P analysis of human eye, retina tissue using GTX71531 mGluR6 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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REFERENCE
There are currently no references for mGluR6 antibody (GTX71531). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for mGluR6 antibody (GTX71531). Be the first to share your experience with this product.
