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mGluR7 antibody

Anti-mGluR7 antibody used in IHC (Paraffin sections) (IHC-P). GTX71715
Anti-mGluR7 antibody used in IHC (Paraffin sections) (IHC-P). GTX71715

Cat No. GTX71715

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P

Reactivity

Human, Mouse, Rat, Rabbit, Bovine, Dog, Chicken, Monkey, Horse
Package
25 μg ($269)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 4 - 6 μg/ml
Not tested in other applications.

Calculated MW

102 kDa. ( Note )

Predict Reactivity

Chimpanzee, Gibbon, Gorilla, Marmoset, Opossum, Orangutan, Turkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 16 amino acid peptide from N-terminal extracellular domain of human GRM7 / MGLUR7.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

, GLUR7 , GPRC1G , GRM7 , MGLU7 , MGLUR7 , PPP1R87 , glutamate metabotropic receptor 7 , mGluR7 , Metabotropic Glutamate Receptor 7

Cellular Localization

Cell membrane

Background

L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

Database

Research Area

DATA IMAGES

Anti-mGluR7 antibody used in IHC (Paraffin sections) (IHC-P). GTX71715

GTX71715 IHC-P Image

IHC-P analysis of human brain, cortex tissue using GTX71715 mGluR7 antibody.
Antigen retrieval : Heat-induced antigen retrieval
Dilution : 4-6 μg/ml

Anti-mGluR7 antibody used in IHC (Paraffin sections) (IHC-P). GTX71715

GTX71715 IHC-P Image

IHC-P analysis of human liver tissue using GTX71715 mGluR7 antibody.
Antigen retrieval : Heat-induced antigen retrieval
Dilution : 4-6 μg/ml

REFERENCE

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REVIEW

There are currently no reviews for mGluR7 antibody (GTX71715). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf