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mGluR8 antibody

Anti-mGluR8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71001
Anti-mGluR8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71001
Anti-mGluR8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71001

Cat No. GTX71001

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P

Reactivity

Human, Mouse, Rat, Monkey, Bat, Horse
Package
25 μg ($269)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 7 - 18 μg/ml
Not tested in other applications.

Calculated MW

102 kDa. ( Note )

Predict Reactivity

Chicken, Baboon, Chimpanzee, Marmoset, Opossum, Shrew, Xenopus, Platypus, Stickleback, Armadillo, Galago(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.79 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 19 amino acid peptide from C-terminus of human GRM8 / MGLUR8.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

glutamate metabotropic receptor 8 , GLUR8 , GPRC1H , GRM8 , MGLUR8 , mGlu8 , mGluR8 , Metabotropic Glutamate Receptor 8

Cellular Localization

Cell membrane

Background

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-mGluR8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71001

GTX71001 IHC-P Image

IHC-P analysis of human brain, neurons and glia tissue using GTX71001 mGluR8 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-mGluR8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71001

GTX71001 IHC-P Image

IHC-P analysis of human pancreas, carcinoma tissue using GTX71001 mGluR8 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-mGluR8 antibody used in IHC (Paraffin sections) (IHC-P). GTX71001

GTX71001 IHC-P Image

IHC-P analysis of brain, medulla tissue using GTX71001 mGluR8 antibody.

REFERENCE

There are currently no references for mGluR8 antibody (GTX71001). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for mGluR8 antibody (GTX71001). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf