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p120 Catenin antibody [6H11]

Cat. No. GTX11508

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 6H11

Isotype

 IgG1

Application

 WB, ICC/IF, IP, ELISA

Reactivity

 Human, Mouse, Rat, Bovine, Dog, Chicken
Package
50 μl ($399)
See all p120 Catenin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:10,000
ICC/IF 1:100
IP Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

105 kDa. ( Note )

Positive Control

chicken fibroblast, MDCK

Product Note

Reacts specifically with the N-terminal region of p120ctn and recognizes isoforms 1 and 2, but not isoforms 3 or 4. In immunoblotting, the antibody recognizes a 120 kDa band, and an additional very weak doublet at 200 kDa.

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Mouse

Immunogen

recombinant N-terminal fragment of murine p120ctn.[1]

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

catenin (cadherin associated protein), delta 1 , AA409437 , AU019353 , Catns , Ctnnd , P120 , mKIAA0384

Cellular Localization

Cytoplasm,Nucleus,Cell membrane

Background

delta 1 Catenin is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.

Database

Research Area

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399