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p18 INK4c antibody

Anti-p18 INK4c antibody used in IHC (Paraffin sections) (IHC-P). GTX55735
Anti-p18 INK4c antibody used in IHC (Paraffin sections) (IHC-P). GTX55735
Anti-p18 INK4c antibody used in IHC (Paraffin sections) (IHC-P). GTX55735
Anti-p18 INK4c antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55735
Anti-p18 INK4c antibody used in Western Blot (WB). GTX55735

Cat. No. GTX55735

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all p18 INK4c products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:100
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

18 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-168 of human CDKN2C (NP_523240.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cyclin dependent kinase inhibitor 2C , INK4C , p18 , p18-INK4C

Background

The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-p18 INK4c antibody used in IHC (Paraffin sections) (IHC-P). GTX55735

GTX55735 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX55735 p18 INK4c antibody.
Dilution : 1:100

Anti-p18 INK4c antibody used in IHC (Paraffin sections) (IHC-P). GTX55735

GTX55735 IHC-P Image

IHC-P analysis of rat lung tissue using GTX55735 p18 INK4c antibody.
Dilution : 1:100

Anti-p18 INK4c antibody used in IHC (Paraffin sections) (IHC-P). GTX55735

GTX55735 IHC-P Image

IHC-P analysis of human stomach tissue using GTX55735 p18 INK4c antibody.
Dilution : 1:100

Anti-p18 INK4c antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55735

GTX55735 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX55735 p18 INK4c antibody.
Blue : DAPI

Anti-p18 INK4c antibody used in Western Blot (WB). GTX55735

GTX55735 WB Image

WB analysis of various sample lysates using GTX55735 p18 INK4c antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399