p53 antibody [SP5]

Cat No. GTX16665

Host	Rabbit
Clonality	Monoclonal
Clone Name	SP5
Application	WB, IHC-P, IHC
Reactivity	Human
Package	500 μl ($369)

See all p53 products

Datasheet
Document

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	Assay dependent
IHC-P	Assay dependent
IHC	Assay dependent

Not tested in other applications.

Calculated MW

44 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full length protein (Human).

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

tumor protein p53 , BCC7 , BMFS5 , LFS1 , P53 , TRP53

Cellular Localization

Cytoplasm , Nucleus , Endoplasmic reticulum , Mitochondrion matrix

Background

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Database

Gene ID: 7157 TP53
UniProt: P04637 TP53

Research Area

DATA IMAGES

GTX16665 IHC Image

Human Lung Adenocarcinoma stained with anti-p53 antibody

GTX16665 IHC Image

Human B Cell Lymphoma stained with anti-p53 antibody

GTX16665 IHC Image

Human Colon Adenocarcinoma stained with anti-p53 antibody

GTX16665 IHC Image

Human Hepatocellular Cell Carcinoma stained with anti-p53 antibody

GTX16665 IHC Image

Human Lung Adenocarcinoma stained with anti-p53 antibody

GTX16665 IHC Image

Human Stomach Adenocarcinoma stained with anti-p53 antibody

GTX16665 IHC Image

Human Breast Ductal Cell Carcinoma stained with anti-p53 antibody

GTX16665 IHC Image

Human Ovarian Adenocarcinoma stained with anti-p53 antibody

GTX16665 IHC Image

Human Bladder Transitional Cell Carcinoma stained with anti-p53 antibody

GTX16665 IHC Image

Human Cervical Squamous Cell Carcinoma stained with anti-p53 antibody

REFERENCE

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REVIEW

There are currently no reviews for p53 antibody [SP5] (GTX16665). Be the first to share your experience with this product.

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SDS
Sodium Azide.pdf

Package

List Price ($)

500 μl

$ 369

Qty

p53 antibody [SP5]

Cat No. GTX16665

Host

Clonality

Clone Name

Application

Reactivity

APPLICATION

Application Note

Calculated MW

PROPERTIES

Form

Buffer

Preservative

Storage

Concentration

Antigen Species

Immunogen

Purification

Conjugation

Note

TARGET

Synonyms

Cellular Localization

Background

Database

Research Area

DATA IMAGES

GTX16665 IHC Image

GTX16665 IHC Image

GTX16665 IHC Image

GTX16665 IHC Image

GTX16665 IHC Image

GTX16665 IHC Image

GTX16665 IHC Image

GTX16665 IHC Image

GTX16665 IHC Image

GTX16665 IHC Image

REFERENCE

REVIEW

Product

Research

Support

Company

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