GeneTex

  • Country / Location Selection

United States (US)

p53R2 peptide

Cat. No. GTX26237

Application

 Neutralizing/Inhibition

Species

 Human
Package
50 μg ($139)
See all p53R2 products

APPLICATION

Application Note

The peptide is used for blocking the antibody activity of anti-p53R2 (cat. no 8105). It usually blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37ºC.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA

Preservative

0.02% Sodium azide

Storage

Store the peptide at -20ºC, stable for one year.

Concentration

0.20 mg/ml (Please refer to the vial label for the specific concentration.)

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Ribonucleotide Reductase Regulatory Tp53 Inducible Subunit M2B , Mtdps8A , Mtdps8B , P53R2 , Rrm2B

Background

The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 signaling, including p53R2, Chk2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered. p53R2 is a p53 inducible gene that contains a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase. p53R2 is induced by ultraviolet and g-irradiation that cause DNA damage. The product of p53R2 gene is directly involved in the p53 checkpoint for repair of damaged DNA. The isoform of the p53 family member p73 also induces p53R2 expression. p53R2 is an important target of p53 for tumour suppression.

Research Area

REFERENCE

There are currently no references for p53R2 peptide (GTX26237). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for p53R2 peptide (GTX26237). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 139