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p67phox antibody

Anti-p67phox antibody used in Western Blot (WB). GTX54565
Anti-p67phox antibody used in IHC (Paraffin sections) (IHC-P). GTX54565

Cat. No. GTX54565

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all p67phox products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

60 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 227-526 of human NCF2 (NP_000424.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887863

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

neutrophil cytosolic factor 2 , NCF-2 , NOXA2 , P67-PHOX , P67PHOX

Cellular Localization

Cytoplasm

Background

This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010]

Database

Research Area

DATA IMAGES

Anti-p67phox antibody used in Western Blot (WB). GTX54565

GTX54565 WB Image

WB analysis of various sample lysates using GTX54565 p67phox antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-p67phox antibody used in IHC (Paraffin sections) (IHC-P). GTX54565

GTX54565 IHC-P Image

IHC-P analysis of human esophageal cancer tissue using GTX54565 p67phox antibody.
Dilution : 1:100

REFERENCE

Application Reference

Richter B et al. Pflugers Arch 2016; 468 (9) : 1621-35 Klotho modulates FGF23-mediated NO synthesis and oxidative stress in human coronary artery endothelial cells.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399