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p70 S6K antibody [1C7]

Anti-p70 S6K antibody [1C7] used in IHC (Paraffin sections) (IHC-P). GTX34178
Anti-p70 S6K antibody [1C7] used in IHC (Paraffin sections) (IHC-P). GTX34178

Cat No. GTX34178

Host Mouse
Clonality Monoclonal
Clone Name 1C7
Isotype IgG1
Application IHC-P
Reactivity Human, Mouse, Rat
Package
100 μl ($319)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

59 kDa. ( Note )

Specificity/Sensitivity

P70 S6 Kinase Mouse Monoclonal Antibody (1C7) detects endogenous levels of RPS6KB1
PROPERTIES

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant Protein of P70 S6 Kinase

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Ribosomal Protein S6 Kinase B1 , Ps6K , S6K , S6K-Beta-1 , S6K1 , Stk14A , P70 S6Ka , P70(S6K)-Alpha , P70-S6K , P70-Alpha , Rps6Kb1

Background

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]

Database

Research Area

DATA IMAGES
Anti-p70 S6K antibody [1C7] used in IHC (Paraffin sections) (IHC-P). GTX34178

GTX34178 IHC-P Image

Immunohistochemistry (IHC) analysis of paraffin-embedded Human Breast Carcinoma Tissue using P70 S6 Kinase Mouse Monoclonal Antibody diluted at 1:200.

Anti-p70 S6K antibody [1C7] used in IHC (Paraffin sections) (IHC-P). GTX34178

GTX34178 IHC-P Image

Immunohistochemistry (IHC) analysis of paraffin-embedded Human Lung Carcinoma Tissue using P70 S6 Kinase Mouse Monoclonal Antibody diluted at 1:200.

REFERENCE
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REVIEW
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Package List Price ($)
$ 319