*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
293T , A431 , Jurkat , Raji , HeLa
Rabbit, Bovine, Chicken, Xenopus laevis(>80% identity)
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.37mg/ml(Please refer to the vial label for the specific concentration.)
Recombinant protein encompassing a sequence within the center region of human p70 S6K. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
PS6K antibody, S6K antibody, S6K1 antibody, STK14A antibody, p70(S6K)-alpha antibody, p70-S6K antibody, p70-alpha antibody, RPS6KB1 antibody, ribosomal protein S6 kinase I antibody, "p70 S6 kinase, alpha 1 antibody", serine/threonine kinase 14 alpha antibody, serine/threonine-protein kinase 14A antibody, p70 S6KA antibody, P70S6K1 antibody, 70 kDa ribosomal protein S6 kinase 1 antibody, "p70 S6 kinase, alpha 2 antibody", ribosomal protein S6 kinase beta-1 antibody, p70 S6K-alpha antibody, S6K-beta-1 antibody, "ribosomal protein S6 kinase, 70kDa, polypeptide 1 antibody"
Cytoplasm (By similarity) , Cell junction , synapse , synaptosome
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized. [provided by RefSeq]