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p70 S6K antibody

Anti-p70 S6K antibody used in Western Blot (WB). GTX50582
Anti-p70 S6K antibody used in IHC (Paraffin sections) (IHC-P). GTX50582
Anti-p70 S6K antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX50582

Cat. No. GTX50582

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human
Package
100 μl ($399)
See all p70 S6K products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
ICC/IF 1:100-1:200
IHC-P 1:50-1:100
Not tested in other applications.

Calculated MW

59 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide sequence around aa. 409~413 (I-R-S-P-R) derived from human p70 S6K.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ribosomal protein S6 kinase B1 , PS6K , S6K , S6K-beta-1 , S6K1 , STK14A , p70 S6KA , p70(S6K)-alpha , p70-S6K , p70-alpha

Cellular Localization

Mitochondrion outer membrane,Mitochondrion,Cytoplasm

Background

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]

Database

Research Area

DATA IMAGES

Anti-p70 S6K antibody used in Western Blot (WB). GTX50582

GTX50582 WB Image

WB analysis of extracts from 293 cells using GTX50582 p70 S6K antibody.

Anti-p70 S6K antibody used in IHC (Paraffin sections) (IHC-P). GTX50582

GTX50582 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX50582 p70 S6K antibody.
Left : Primary antibody
Right : Primary antibody pre-incubated with the antigen specific peptide

Anti-p70 S6K antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX50582

GTX50582 ICC/IF Image

ICC/IF analysis of methanol-fixed MCF-7 cells using GTX50582 p70 S6K antibody.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399