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p73 antibody [5B789]

Anti-p73 antibody [5B789] used in Western Blot (WB). GTX13818

Cat. No. GTX13818

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 5B789

Isotype

 IgG1

Application

 WB

Reactivity

 Human
Package
200 μl ($399)
See all p73 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 3 μg/ml
Not tested in other applications.

Calculated MW

70 kDa. ( Note )

Product Note

This antibody does not cross react with mouse p73 or with p53.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

This antibody was raised against full-length human p73. IMG-260 reacts with an epitope that is located on the C-terminal region of human p73 only. It does not cross react with mouse p73 or with p53.

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

tumor protein p73 , P73

Cellular Localization

Nucleus,Cytoplasm

Background

This gene encodes tumor protein p73, which is a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include p53, p63, and p73 and have high sequence similarity to one another, which allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways involving direct or indirect protein interactions, resulting in regulation of the same target gene promoters or regulation of each other's promoters. The p73 protein is expressed at very low levels in normal tissues and is differentially expressed in a number of tumors. The p73 gene expresses at least 35 mRNA variants due to the use of alternate promoters, alternate translation initiation sites, and multiple splice variations. Theoretically this can account for 29 different p73 isoforms; however, the biological validity and the full-length nature of most variants have not been determined. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-p73 antibody [5B789] used in Western Blot (WB). GTX13818

GTX13818 WB Image

WB analysis of RH30 cell lysate using GTX13818 p73 antibody [5B789].
Dilution : 2 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399