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p90 RSK1 (phospho Thr359/Ser363) antibody [RM233]

Anti-p90 RSK1 (phospho Thr359/Ser363) antibody [RM233] used in Western Blot (WB). GTX33600
Anti-p90 RSK1 (phospho Thr359/Ser363) antibody [RM233] used in IHC (Paraffin sections) (IHC-P). GTX33600

Cat No. GTX33600

Host

Rabbit

Clonality

Monoclonal

Clone Name

RM233

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human
Package
100 μl ($279)

APPLICATION

Application Note

Immunohistochemistry (IHC): 1:1000-1:2000 dilution, Western Blot (WB): 1:200-1:500 dilution.

Calculated MW

83 kDa. ( Note )

Specificity/Sensitivity

This antibody reacts to human RSK1 only when phosphorylated at Thr359/Ser363.

PROPERTIES

Form

Liquid

Buffer

50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A phospho-peptide corresponding to human phospho-Rsk1 (Thr359/Ser363)

Purification

Protein A affinity purified from an animal origin-free culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Ribosomal Protein S6 Kinase A1 , Hu-1 , Mapkapk1A , Rsk , Rsk1 , P90Rsk , Rps6Ka1

Background

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-p90 RSK1 (phospho Thr359/Ser363) antibody [RM233] used in Western Blot (WB). GTX33600

GTX33600 WB Image

Western Blot of A431 cells treated (+) or nontreated (-) with EGF, using Anti-phospho-Rsk1 (Thr359/Ser363) RM233 at a 1:1000 dilution, showed a band of phospho-rylated Rsk1 only in EGF treated A431 cells .

Anti-p90 RSK1 (phospho Thr359/Ser363) antibody [RM233] used in IHC (Paraffin sections) (IHC-P). GTX33600

GTX33600 IHC-P Image

Immunohistochemical staining of formalin fixed and paraffin embedded human cerebral cortex tissue sections using Anti-phospho-Rsk1 (Thr359/Ser363) RM233 at a 1:200 dilution.

REFERENCE

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REVIEW

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Package List Price ($)
$ 279