GeneTex
United States (US)

proBNP antibody [B915M], N-term

Cat No. GTX39517

Host Mouse
Clonality Monoclonal
Clone Name B915M
Isotype IgG1
Application WB, ELISA, sELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ELISA Assay dependent
sELISA Assay dependent
Not tested in other applications.

Calculated MW

15 kDa. ( Note )

Specificity/Sensitivity

Human proBNP and NT-proBNP (recombinant and synthetic) (a.a. 13–27).
PROPERTIES

Form

Liquid

Buffer

PBS pH 7.4, 0.09% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

6 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide corresponding to amino acids 13–27 of the proBNP sequence

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Natriuretic Peptide B,Bnp,Nppb

Background

This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Nov 2014]

Database

Research Area